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Evidence of neurodegeneration in autism spectrum disorder

Overview of attention for article published in Translational Neurodegeneration, August 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)

Mentioned by

twitter
4 tweeters
peer_reviews
1 peer review site
facebook
1 Facebook page

Citations

dimensions_citation
49 Dimensions

Readers on

mendeley
97 Mendeley
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Title
Evidence of neurodegeneration in autism spectrum disorder
Published in
Translational Neurodegeneration, August 2013
DOI 10.1186/2047-9158-2-17
Pubmed ID
Authors

Janet K Kern, David A Geier, Lisa K Sykes, Mark R Geier

Abstract

Autism spectrum disorder (ASD) is a neurological disorder in which a significant number of children experience a developmental regression characterized by a loss of previously-acquired skills and abilities. Loss of neurological function in ASD, as observed in affected children who have regressed, can be explained as neurodegeneration. Although there is research evidence of neurodegeneration or progressive encephalopathy in ASD, the issue of neurodegeneration in ASD is still under debate. Evidence of neurodegeneration in the brain in ASD includes: (1) neuronal cell loss, (2) activated microglia and astrocytes, (3) proinflammatory cytokines, (4) oxidative stress, and (5) elevated 8-oxo-guanosine levels. The evidence from this review suggests that neurodegeneration underlies the loss of neurological function in children with ASD who have experienced regression and loss of previously acquired skills and abilities, and that research into treatments to address the issue of neurodegeneration in ASD are warranted.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Brazil 1 1%
Unknown 95 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 18%
Student > Bachelor 17 18%
Student > Master 15 15%
Researcher 12 12%
Student > Doctoral Student 9 9%
Other 15 15%
Unknown 12 12%
Readers by discipline Count As %
Medicine and Dentistry 17 18%
Agricultural and Biological Sciences 16 16%
Psychology 13 13%
Neuroscience 12 12%
Biochemistry, Genetics and Molecular Biology 8 8%
Other 16 16%
Unknown 15 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2017.
All research outputs
#4,603,710
of 16,581,438 outputs
Outputs from Translational Neurodegeneration
#132
of 212 outputs
Outputs of similar age
#33,950
of 129,413 outputs
Outputs of similar age from Translational Neurodegeneration
#1
of 1 outputs
Altmetric has tracked 16,581,438 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 212 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.5. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,413 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them