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Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells

Overview of attention for article published in BMC Complementary Medicine and Therapies, August 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#39 of 3,756)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
3 news outlets
twitter
26 X users
facebook
1675 Facebook pages
googleplus
6 Google+ users
video
1 YouTube creator

Citations

dimensions_citation
170 Dimensions

Readers on

mendeley
386 Mendeley
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Title
Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells
Published in
BMC Complementary Medicine and Therapies, August 2013
DOI 10.1186/1472-6882-13-212
Pubmed ID
Authors

Liron Berkovich, Gideon Earon, Ilan Ron, Adam Rimmon, Akiva Vexler, Shahar Lev-Ari

Abstract

Fewer than 6% patients with adenocarcinoma of the pancreas live up to five years after diagnosis. Chemotherapy is currently the standard treatment, however, these tumors often develop drug resistance over time. Agents for increasing the cytotoxic effects of chemotherapy or reducing the cancer cells' chemo-resistance to the drugs are required to improve treatment outcome. Nuclear factor kappa B (NF-kB), a pro-inflammatory transcription factor, reportedly plays a significant role in the resistance of pancreatic cancer cells to apoptosis-based chemotherapy. This study investigated the effect of aqueous Moringa Oleifera leaf extract on cultured human pancreatic cancer cells - Panc-1, p34, and COLO 357, and whether it can potentiates the effect of cisplatin chemotherapy on these cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 26 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 386 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
India 1 <1%
China 1 <1%
Unknown 383 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 58 15%
Student > Master 52 13%
Student > Ph. D. Student 45 12%
Student > Doctoral Student 22 6%
Researcher 18 5%
Other 57 15%
Unknown 134 35%
Readers by discipline Count As %
Agricultural and Biological Sciences 65 17%
Biochemistry, Genetics and Molecular Biology 42 11%
Medicine and Dentistry 34 9%
Pharmacology, Toxicology and Pharmaceutical Science 30 8%
Chemistry 18 5%
Other 52 13%
Unknown 145 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 170. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2023.
All research outputs
#217,850
of 23,896,578 outputs
Outputs from BMC Complementary Medicine and Therapies
#39
of 3,756 outputs
Outputs of similar age
#1,546
of 202,313 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#2
of 89 outputs
Altmetric has tracked 23,896,578 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,756 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,313 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.