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The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

Overview of attention for article published in Journal of Neuroinflammation, June 2013
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Title
The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion
Published in
Journal of Neuroinflammation, June 2013
DOI 10.1186/1742-2094-10-75
Pubmed ID
Authors

Starlee Lively, Lyanne C Schlichter

Abstract

Microglial cells are highly mobile under many circumstances and, after central nervous system (CNS) damage, they must contend with the dense extracellular matrix (ECM) in order to reach their target sites. In response to damage or disease, microglia undergo complex activation processes that can be modulated by environmental cues and culminate in either detrimental or beneficial outcomes. Thus, there is considerable interest in comparing their pro-inflammatory ('classical' activation) and resolving 'alternative' activation states. Almost nothing is known about how these activation states affect the ability of microglia to migrate and degrade ECM, or the enzymes used for substrate degradation. This is the subject of the present study.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 266 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Australia 1 <1%
Brazil 1 <1%
Sweden 1 <1%
Romania 1 <1%
United States 1 <1%
Serbia 1 <1%
Unknown 259 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 53 20%
Student > Master 46 17%
Student > Bachelor 37 14%
Researcher 34 13%
Student > Doctoral Student 27 10%
Other 32 12%
Unknown 37 14%
Readers by discipline Count As %
Neuroscience 61 23%
Agricultural and Biological Sciences 54 20%
Biochemistry, Genetics and Molecular Biology 35 13%
Medicine and Dentistry 24 9%
Engineering 10 4%
Other 32 12%
Unknown 50 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2013.
All research outputs
#15,276,424
of 22,716,996 outputs
Outputs from Journal of Neuroinflammation
#1,736
of 2,613 outputs
Outputs of similar age
#121,981
of 196,855 outputs
Outputs of similar age from Journal of Neuroinflammation
#17
of 38 outputs
Altmetric has tracked 22,716,996 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,613 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,855 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.