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Mendeley readers
Attention Score in Context
| Title |
Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines
|
|---|---|
| Published in |
Cancer Cell International, July 2013
|
| DOI | 10.1186/1475-2867-13-77 |
| Pubmed ID | |
| Authors |
Xueqing Wang, Lingya Pan, Ning Mao, Lifang Sun, Xiangjuan Qin, Jie Yin |
| Abstract |
Taxol is a powerful chemotherapy agent leading to mitotic arrest and cell death; however, its clinical efficacy has been hampered due to the development of drug resistance. Taxol specifically targets the cell cycle. Progress through mitosis (M stage) is an absolute requirement for drug-induced death because cell death is markedly reduced in cells blocked at the G1-S transition. The measured doubling time for ovarian cancer cells is about 27 h. As such, during treatment with Taxol most of the cells are not in the M stage of the cell cycle. Thus, the effect of cell-cycle synchronization was investigated in regard to reversing Taxol resistance in ovarian cancer cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 44 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 22% |
| Researcher | 7 | 16% |
| Student > Bachelor | 7 | 16% |
| Student > Doctoral Student | 4 | 9% |
| Student > Postgraduate | 3 | 7% |
| Other | 8 | 18% |
| Unknown | 6 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 27% |
| Biochemistry, Genetics and Molecular Biology | 12 | 27% |
| Medicine and Dentistry | 6 | 13% |
| Engineering | 2 | 4% |
| Environmental Science | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 8 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2013.
All research outputs
#20,198,525
of 22,716,996 outputs
Outputs from Cancer Cell International
#1,343
of 1,789 outputs
Outputs of similar age
#174,169
of 198,191 outputs
Outputs of similar age from Cancer Cell International
#5
of 6 outputs
Altmetric has tracked 22,716,996 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,789 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,191 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.