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l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity…

Overview of attention for article published in Behavioral and Brain Functions, January 2008
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Title
l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)
Published in
Behavioral and Brain Functions, January 2008
DOI 10.1186/1744-9081-4-3
Pubmed ID
Authors

Terje Sagvolden, Tong Xu

Abstract

ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinical symptoms. There is no biological marker, but there is considerable evidence to suggest that ADHD behavior is associated with poor dopaminergic and noradrenergic modulation of neuronal circuits that involve the frontal lobes. The best validated animal model of ADHD, the Spontaneously Hypertensive Rat (SHR), shows pronounced overactivity, impulsiveness, and deficient sustained attention. While dopamine release is decreased in SHR, norepinephrine concentrations are elevated. The primary objective of the present research was to test effects of a range of doses of the catecholamine agonists d- and l-amphetamine on ADHD-like symptoms in SHR.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
United Kingdom 1 1%
Mexico 1 1%
South Africa 1 1%
Unknown 74 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 18%
Researcher 11 14%
Student > Bachelor 10 13%
Student > Master 8 10%
Student > Doctoral Student 6 8%
Other 20 25%
Unknown 10 13%
Readers by discipline Count As %
Psychology 17 22%
Agricultural and Biological Sciences 13 16%
Medicine and Dentistry 11 14%
Neuroscience 7 9%
Biochemistry, Genetics and Molecular Biology 4 5%
Other 10 13%
Unknown 17 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2013.
All research outputs
#19,280,745
of 21,666,161 outputs
Outputs from Behavioral and Brain Functions
#323
of 383 outputs
Outputs of similar age
#154,150
of 177,036 outputs
Outputs of similar age from Behavioral and Brain Functions
#1
of 1 outputs
Altmetric has tracked 21,666,161 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 383 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 177,036 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them