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Procalcitonin beyond the acute phase: novel biomediator properties?

Overview of attention for article published in BMC Medicine, August 2013
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Title
Procalcitonin beyond the acute phase: novel biomediator properties?
Published in
BMC Medicine, August 2013
DOI 10.1186/1741-7015-11-189
Pubmed ID
Authors

Carolina Panico, Eric Nylen

Abstract

Since inflammation has been linked to carcinogenic events, discovery of relevant biomarkers may have important preventative implications. Procalcitonin (ProCT) has been shown to be an important prognostic biomarker in severe inflammatory conditions, but there is no data regarding its biomarker role, if any, beyond the acute phase. In a recent study published in BMC Medicine, Cotoi et al. analyzed whether serum ProCT levels in healthy individuals are associated with mortality outcomes. The results are affirmative in that baseline ProCT was shown to be strongly and independently associated with all-cause and cancer mortality and with the incidence of colon cancer in men. By contrast, the study indicated that high sensitivity C-reactive protein was independently associated with cardiovascular mortality but not with cancer mortality in men. Thus, baseline levels of ProCT appear to have prognostic biomarker implications potentially related to its emerging biomediator action(s).

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 25%
Student > Ph. D. Student 4 25%
Researcher 3 19%
Unspecified 1 6%
Student > Master 1 6%
Other 0 0%
Unknown 3 19%
Readers by discipline Count As %
Medicine and Dentistry 4 25%
Immunology and Microbiology 2 13%
Agricultural and Biological Sciences 2 13%
Unspecified 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 3 19%
Unknown 3 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2014.
All research outputs
#15,278,165
of 22,719,618 outputs
Outputs from BMC Medicine
#3,033
of 3,410 outputs
Outputs of similar age
#123,592
of 200,072 outputs
Outputs of similar age from BMC Medicine
#55
of 56 outputs
Altmetric has tracked 22,719,618 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.5. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,072 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.