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Mendeley readers
Attention Score in Context
| Title |
Anti-diabetic and anti-oxidant potential of aged garlic extract (AGE) in streptozotocin-induced diabetic rats
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, January 2016
|
| DOI | 10.1186/s12906-016-0992-5 |
| Pubmed ID | |
| Authors |
Martha Thomson, Khaled K. Al-Qattan, Divya JS, Muslim Ali |
| Abstract |
Although aged garlic extract (AGE) shares some active components with fresh garlic and in spite of its palatability and milder side effects, the anti-diabetic and related anti-oxidant properties of AGE have not been investigated extensively, and the reported findings are inconsistent. This study investigated the anti-diabetic effects of 3 incremental doses of AGE in streptozotocin (STZ)-induced diabetic rats (fasting blood sugar > 20 mM). Diabetic rats were divided into a control diabetic group (CD) and AGE-treated diabetic group (AGE-D). The AGE-D was divided into 3 groups and accordingly treated with AGE i.p. at 100, 300 and 600 mg/kg daily for 8 weeks. A control normal group (CN) was also included for reference. Compared to the CN group, the CD group showed significant loss of body weight (over 50 %); and decreased serum insulin concentration (10 fold) and total anti-oxidant level and catalase activity (45-70 %) in serum, kidney and liver. Conversely, the CD rats had an elevated blood glucose (nearly 4 fold), serum cholesterol (nearly 2 fold) and triglycerides (>2 fold), erythrocyte glycated hemoglobin (GHb, 3 fold) and kidney and liver lipid peroxidation (MDA levels). Treatment with AGE positively reversed the diabetic changes in the targeted parameters to levels significantly lower than those measured in the CD group and the degrees of attenuation were almost dose dependent especially with the two higher doses. AGE exhibits a dose-dependent ameliorative action on indicators of diabetes in STZ-induced diabetic rats. |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 153 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 21 | 14% |
| Student > Bachelor | 20 | 13% |
| Researcher | 14 | 9% |
| Student > Ph. D. Student | 10 | 7% |
| Student > Doctoral Student | 7 | 5% |
| Other | 32 | 21% |
| Unknown | 49 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 13% |
| Medicine and Dentistry | 20 | 13% |
| Agricultural and Biological Sciences | 14 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 8% |
| Chemistry | 9 | 6% |
| Other | 20 | 13% |
| Unknown | 57 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2021.
All research outputs
#1,880,066
of 22,958,253 outputs
Outputs from BMC Complementary Medicine and Therapies
#331
of 3,638 outputs
Outputs of similar age
#35,273
of 395,160 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#10
of 79 outputs
Altmetric has tracked 22,958,253 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,638 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,160 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.