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Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells

Overview of attention for article published in BMC Cancer, August 2013
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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3 X users

Citations

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48 Mendeley
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Title
Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells
Published in
BMC Cancer, August 2013
DOI 10.1186/1471-2407-13-391
Pubmed ID
Authors

Babu V Sajesh, Zelda Lichtensztejn, Kirk J McManus

Abstract

Chromosome instability manifests as an abnormal chromosome complement and is a pathogenic event in cancer. Although a correlation between abnormal chromosome numbers and cancer exist, the underlying mechanisms that cause chromosome instability are poorly understood. Recent data suggests that aberrant sister chromatid cohesion causes chromosome instability and thus contributes to the development of cancer. Cohesion normally functions by tethering nascently synthesized chromatids together to prevent premature segregation and thus chromosome instability. Although the prevalence of aberrant cohesion has been reported for some solid tumors, its prevalence within liquid tumors is unknown. Consequently, the current study was undertaken to evaluate aberrant cohesion within Hodgkin lymphoma, a lymphoid malignancy that frequently exhibits chromosome instability.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 23%
Student > Ph. D. Student 8 17%
Researcher 7 15%
Student > Master 5 10%
Student > Doctoral Student 4 8%
Other 4 8%
Unknown 9 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 33%
Agricultural and Biological Sciences 11 23%
Medicine and Dentistry 7 15%
Engineering 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 9 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2013.
All research outputs
#12,764,497
of 22,719,618 outputs
Outputs from BMC Cancer
#2,678
of 8,267 outputs
Outputs of similar age
#99,294
of 198,610 outputs
Outputs of similar age from BMC Cancer
#26
of 69 outputs
Altmetric has tracked 22,719,618 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,267 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,610 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.