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Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

Overview of attention for article published in BMC Cancer, August 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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4 X users
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1 patent

Citations

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108 Dimensions

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108 Mendeley
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Title
Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island
Published in
BMC Cancer, August 2013
DOI 10.1186/1471-2407-13-398
Pubmed ID
Authors

Reinhold Wasserkort, Alexandra Kalmar, Gabor Valcz, Sandor Spisak, Manuel Krispin, Kinga Toth, Zsolt Tulassay, Andrew Z Sledziewski, Bela Molnar

Abstract

The septin 9 gene (SEPT9) codes for a GTP-binding protein associated with filamentous structures and cytoskeleton formation. SEPT9 plays a role in multiple cancers as either an oncogene or a tumor suppressor gene. Regulation of SEPT9 expression is complex and not well understood; however, hypermethylation of the gene was recently introduced as a biomarker for early detection of colorectal cancer (CRC) and has been linked to cancer of the breast and of the head and neck. Because the DNA methylation landscape of different regions of SEPT9 is poorly understood in cancer, we analyzed the methylation patterns of this gene in distinct cell populations from normal and diseased colon mucosa.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
Ukraine 1 <1%
Germany 1 <1%
Unknown 104 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 21%
Student > Ph. D. Student 18 17%
Student > Master 12 11%
Student > Bachelor 8 7%
Other 5 5%
Other 17 16%
Unknown 25 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 25%
Medicine and Dentistry 19 18%
Biochemistry, Genetics and Molecular Biology 17 16%
Unspecified 3 3%
Nursing and Health Professions 3 3%
Other 12 11%
Unknown 27 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2020.
All research outputs
#6,464,424
of 23,989,432 outputs
Outputs from BMC Cancer
#1,586
of 8,531 outputs
Outputs of similar age
#53,390
of 203,459 outputs
Outputs of similar age from BMC Cancer
#16
of 71 outputs
Altmetric has tracked 23,989,432 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 8,531 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 203,459 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.