Title |
The protocol for a randomised controlled trial comparing intermittent and graded exercise to usual care for chronic fatigue syndrome patients
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Published in |
BMC Sports Science, Medicine and Rehabilitation, August 2013
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DOI | 10.1186/2052-1847-5-16 |
Pubmed ID | |
Authors |
Suzanne Broadbent, Rosanne Coutts |
Abstract |
Chronic Fatigue Syndrome is a debilitating disorder with an unknown aetiology but suspected multifactorial origins. Common "triggers" include severe viral infections and emotional stress. Recent studies have also found evidence of immune dysfunction and elevated inflammatory cytokines in CFS patients, but there has been considerable variation in the outcome measures and magnitude of these studies. Currently, there is no cure for CFS but treatments include rest, specialist medical care, cognitive behavioural therapy, and graded (self-paced) exercise. To date, several studies have examined the efficacy of graded exercise with or without Cognitive Behavioural Therapy, with some success for patients. However, improvements in functional capacity have not necessarily correlated with improvements in immune function, fatigue or other symptoms. This 12-week pilot trial compares graded and intermittent exercise to normal care, measuring physiological outcomes, fatigue levels, immune function and wellness. |
X Demographics
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United Kingdom | 2 | 40% |
Australia | 1 | 20% |
Unknown | 2 | 40% |
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Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
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Italy | 1 | <1% |
Canada | 1 | <1% |
Unknown | 99 | 98% |
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Student > Ph. D. Student | 16 | 16% |
Student > Doctoral Student | 12 | 12% |
Student > Master | 10 | 10% |
Researcher | 8 | 8% |
Other | 13 | 13% |
Unknown | 20 | 20% |
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Agricultural and Biological Sciences | 6 | 6% |
Other | 11 | 11% |
Unknown | 24 | 24% |