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Acute Adrenal Crisis in an Asthmatic Child Treated with Inhaled Fluticasone Proprionate

Overview of attention for article published in International Journal of Pediatric Endocrinology, July 2010
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Title
Acute Adrenal Crisis in an Asthmatic Child Treated with Inhaled Fluticasone Proprionate
Published in
International Journal of Pediatric Endocrinology, July 2010
DOI 10.1155/2010/749239
Pubmed ID
Authors

Angela H. Santiago, Susan Ratzan

Abstract

Adrenal suppression secondary to prolonged inhaled corticosteroid use is usually limited to biochemical abnormalities, with no obvious clinical effects. Acute adrenal crisis is much rarer event but has been reported with increasing frequency. We report a case of a 7-year-old asthmatic child who presented with an acute history of lethargy after a respiratory infection. He was maintained on 220 mug/day of fluticasone propionate for several years. Initial evaluation revealed severe adrenal suppression, with undetectable cortisol levels and minimal response after stimulation with ACTH. After fluticasone was discontinued, a gradual recovery of the adrenal axis was seen. This case shows that acute adrenal crisis may be a consequence even at the usual prescribed doses, stressing the importance of using the lowest dose of inhaled steroids needed to control symptoms and having an increased awareness of this complication.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 11%
Unknown 16 89%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 22%
Researcher 4 22%
Other 2 11%
Student > Master 2 11%
Student > Ph. D. Student 1 6%
Other 3 17%
Unknown 2 11%
Readers by discipline Count As %
Medicine and Dentistry 11 61%
Nursing and Health Professions 2 11%
Immunology and Microbiology 1 6%
Agricultural and Biological Sciences 1 6%
Unknown 3 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2013.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from International Journal of Pediatric Endocrinology
#128
of 137 outputs
Outputs of similar age
#98,691
of 103,592 outputs
Outputs of similar age from International Journal of Pediatric Endocrinology
#4
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 137 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,592 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.