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Association between blood lead and blood pressure: a population-based study in Brazilian adults

Overview of attention for article published in Environmental Health, March 2017
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Title
Association between blood lead and blood pressure: a population-based study in Brazilian adults
Published in
Environmental Health, March 2017
DOI 10.1186/s12940-017-0233-5
Pubmed ID
Authors

Ana Carolina Bertin de Almeida Lopes, Ellen Kovner Silbergeld, Ana Navas-Acien, Rachel Zamoiski, Airton da Cunha Martins Jr., Alissana Ester Iakmiu Camargo, Mariana Ragassi Urbano, Arthur Eumann Mesas, Monica Maria Bastos Paoliello

Abstract

Environmental lead exposure among adults may increase blood pressure and elevate the risk of hypertension. The availability of data on blood lead levels (BLL) in adult Brazilian population is scarce and population-based studies are important for screening the population exposure and also to evaluate associations with adverse health effects. The goal of this study was to examine the association of BLL with blood pressure and hypertension in a population-based study in a city in Southern Brazil. A total of 948 adults, aged 40 years or older, were randomly selected. Information on socioeconomic, dietary, lifestyle and occupational background was obtained by orally administered household interviews. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured according to the guidelines VI Brazilian Guidelines on Hypertension. BLL were measured by inductively coupled plasma mass spectrometry technique. Multiple linear and logistic regression models were performed to evaluate associations of BLL with SBP and DBP, and with the chance of hypertension and of elevated SBP and DBP. The geometric mean of BLL was 1.97 μg/dL (95%CI:1.90-2.04 μg/dL). After multivariable adjustment, participants in the quartile 4 of blood lead presented 0.06 mm/Hg (95%CI, 0.04-0.09) average difference in DBP comparing with those in quartile 1. Participants in the 90th percentile of blood lead distribution had 0.07 mmHg (95% CI, 0.03 to 0.11) higher DBP compared with those participants in the 10th percentile of blood lead. The adjusted OR for hypertension was 2.54 (95% CI, 1.17-5.53), comparing the highest to the lowest blood lead quartiles. Compared with participants in the 10th percentile of blood lead, participants in the 90th percentile presented higher OR for hypertension (OR: 2.77; 95% CI, 1.41 to 5.46). At low concentrations, BLL were positively associated with DBP and with the odds for hypertension in adults aged 40 or older. It is important to enforce lead exposure monitoring and the enactment of regulatory laws to prevent lead contamination in urban settings.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 78 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 21%
Student > Bachelor 9 12%
Researcher 7 9%
Professor 4 5%
Student > Doctoral Student 3 4%
Other 12 15%
Unknown 27 35%
Readers by discipline Count As %
Medicine and Dentistry 14 18%
Environmental Science 9 12%
Biochemistry, Genetics and Molecular Biology 7 9%
Psychology 3 4%
Chemistry 3 4%
Other 14 18%
Unknown 28 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2018.
All research outputs
#13,468,709
of 22,959,818 outputs
Outputs from Environmental Health
#963
of 1,498 outputs
Outputs of similar age
#158,133
of 307,966 outputs
Outputs of similar age from Environmental Health
#21
of 38 outputs
Altmetric has tracked 22,959,818 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,498 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.3. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,966 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.