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Screening for fecal carriage of MCR-producing Enterobacteriaceae in healthy humans and primary care patients

Overview of attention for article published in Antimicrobial Resistance & Infection Control, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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2 news outlets
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6 X users
googleplus
1 Google+ user

Citations

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47 Dimensions

Readers on

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83 Mendeley
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Title
Screening for fecal carriage of MCR-producing Enterobacteriaceae in healthy humans and primary care patients
Published in
Antimicrobial Resistance & Infection Control, March 2017
DOI 10.1186/s13756-017-0186-z
Pubmed ID
Authors

Katrin Zurfluh, Roger Stephan, Andreas Widmer, Laurent Poirel, Patrice Nordmann, Hans-Jakob Nüesch, Herbert Hächler, Magdalena Nüesch-Inderbinen

Abstract

The extent of the occurrence of the plasmid-encoded colistin resistance genes mcr-1 and mcr-2 among humans is currently sparsely studied in Western Europe. To determine the occurrence of MCR-producing Enterobacteriaceae in fecal samples of healthy humans with high occupational exposure to food and primary care patients in Switzerland. Stool samples from 1091 healthy individuals and fecal swabs from 53 primary care patients were screened for polymyxin-resistant Enterobacteriaceae using LB agar containing 4 mg/L colistin. Minimal inhibitory concentrations (MICs) of colistin were determined for non-intrinsic colistin-resistant isolates. Isolates were screened by PCR for the presence of mcr-1 and mcr-2 genes. The fecal carriage rate of colistin resistant (MIC value >2 mg/l) Enterobacteriaceae was 1.5% for healthy people and 3.8% for primary care patients. Isolates included Hafnia alvei (n = 9), Escherichia coli (n = 3), Enterobacter cloacae (n = 4), Klebsiella pneumoniae (n = 1) and Raoultella ornithinolytica (n = 1). None of the isolates harbored the mcr-1 or mcr-2 genes. There is no evidence for the presence of MCR-producers in the fecal flora of healthy people or primary care patients. Therefore, the risk of transfer of mcr genes from animals, food or the environment to humans is likely to be low in Switzerland.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Unknown 82 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 12%
Student > Ph. D. Student 9 11%
Student > Bachelor 9 11%
Researcher 8 10%
Professor 5 6%
Other 17 20%
Unknown 25 30%
Readers by discipline Count As %
Medicine and Dentistry 15 18%
Immunology and Microbiology 14 17%
Biochemistry, Genetics and Molecular Biology 9 11%
Veterinary Science and Veterinary Medicine 6 7%
Agricultural and Biological Sciences 5 6%
Other 7 8%
Unknown 27 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2017.
All research outputs
#1,725,973
of 24,792,566 outputs
Outputs from Antimicrobial Resistance & Infection Control
#183
of 1,407 outputs
Outputs of similar age
#33,519
of 313,025 outputs
Outputs of similar age from Antimicrobial Resistance & Infection Control
#4
of 23 outputs
Altmetric has tracked 24,792,566 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,407 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,025 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.