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Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae

Overview of attention for article published in Parasites & Vectors, February 2013
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Title
Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae
Published in
Parasites & Vectors, February 2013
DOI 10.1186/1756-3305-6-42
Pubmed ID
Authors

David Wimmersberger, Lucienne Tritten, Jennifer Keiser

Abstract

Trichuriasis represents a major public health problem in the developing world and is regarded as a neglected disease. Albendazole and mebendazole, the two drugs of choice against trichuriasis display only moderate cure rates, hence alternative drugs are needed. To identify candidate compounds, in vitro drug sensitivity testing currently relies on the adult Trichuris muris motility assay. The objective of the present study was to develop a simple and cost-effective drug sensitivity assay using Trichuris muris first-stage larvae (L1).

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
Denmark 1 2%
Switzerland 1 2%
Unknown 41 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 32%
Researcher 9 20%
Student > Bachelor 6 14%
Student > Master 4 9%
Student > Postgraduate 2 5%
Other 5 11%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 32%
Medicine and Dentistry 6 14%
Biochemistry, Genetics and Molecular Biology 5 11%
Veterinary Science and Veterinary Medicine 4 9%
Immunology and Microbiology 3 7%
Other 7 16%
Unknown 5 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2013.
All research outputs
#18,345,822
of 22,719,618 outputs
Outputs from Parasites & Vectors
#4,204
of 5,441 outputs
Outputs of similar age
#146,813
of 192,977 outputs
Outputs of similar age from Parasites & Vectors
#33
of 38 outputs
Altmetric has tracked 22,719,618 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,441 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,977 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.