You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
IRFinder: assessing the impact of intron retention on mammalian gene expression
|
|---|---|
| Published in |
Genome Biology, March 2017
|
| DOI | 10.1186/s13059-017-1184-4 |
| Pubmed ID | |
| Authors |
Robert Middleton, Dadi Gao, Aubin Thomas, Babita Singh, Amy Au, Justin J-L Wong, Alexandra Bomane, Bertrand Cosson, Eduardo Eyras, John E. J. Rasko, William Ritchie |
| Abstract |
Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called IRFinder to accurately detect IR from mRNA sequencing data. Analysis of 2573 samples showed that IR occurs in all tissues analyzed, affects over 80% of all coding genes and is associated with cell differentiation and the cell cycle. Frequently retained introns are enriched for specific RNA binding protein sites and are often retained in clusters in the same gene. IR is associated with lower protein levels and intron-retaining transcripts that escape nonsense-mediated decay are not actively translated. |
X Demographics
The data shown below were collected from the profiles of 32 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 28% |
| Australia | 2 | 6% |
| United Kingdom | 2 | 6% |
| Switzerland | 2 | 6% |
| Bermuda | 1 | 3% |
| Germany | 1 | 3% |
| France | 1 | 3% |
| Unknown | 14 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 20 | 63% |
| Members of the public | 11 | 34% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 290 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Germany | 1 | <1% |
| France | 1 | <1% |
| Unknown | 287 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 77 | 27% |
| Researcher | 49 | 17% |
| Student > Master | 36 | 12% |
| Student > Bachelor | 14 | 5% |
| Student > Doctoral Student | 13 | 4% |
| Other | 40 | 14% |
| Unknown | 61 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 107 | 37% |
| Agricultural and Biological Sciences | 67 | 23% |
| Computer Science | 9 | 3% |
| Neuroscience | 7 | 2% |
| Mathematics | 6 | 2% |
| Other | 27 | 9% |
| Unknown | 67 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 26. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2020.
All research outputs
#1,499,061
of 25,402,528 outputs
Outputs from Genome Biology
#1,196
of 4,470 outputs
Outputs of similar age
#29,284
of 322,251 outputs
Outputs of similar age from Genome Biology
#24
of 59 outputs
Altmetric has tracked 25,402,528 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,470 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,251 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.