Title |
The role of Notch signalling in ovarian angiogenesis
|
---|---|
Published in |
Journal of Ovarian Research, March 2017
|
DOI | 10.1186/s13048-017-0308-5 |
Pubmed ID | |
Authors |
Qi Xie, Zuowang Cheng, Xiaocui Chen, Corrinne G. Lobe, Ju Liu |
Abstract |
In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corpus luteum to receive oxygen, nutrients and hormonal support. Abnormal angiogenesis is involved in the induction and development of pathological ovary, such as polycystic ovary syndrome and ovarian cancer. Notch signalling pathway is one of the primary regulators of angiogenesis and a therapeutic target for ovarian diseases. Here, we will review literatures on the expression pattern of Notch pathway components in the ovary and on the role of Notch signalling pathway on ovarian angiogenesis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 67 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 21% |
Student > Master | 12 | 18% |
Student > Ph. D. Student | 7 | 10% |
Student > Bachelor | 7 | 10% |
Student > Doctoral Student | 2 | 3% |
Other | 8 | 12% |
Unknown | 17 | 25% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 22% |
Biochemistry, Genetics and Molecular Biology | 14 | 21% |
Agricultural and Biological Sciences | 5 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Veterinary Science and Veterinary Medicine | 3 | 4% |
Other | 5 | 7% |
Unknown | 22 | 33% |