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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication
|
|---|---|
| Published in |
Retrovirology, September 2013
|
| DOI | 10.1186/1742-4690-10-96 |
| Pubmed ID | |
| Authors |
Guerline Clerzius, Eileen Shaw, Aïcha Daher, Samantha Burugu, Jean-François Gélinas, Thornin Ear, Lucile Sinck, Jean-Pierre Routy, Andrew J Mouland, Rekha C Patel, Anne Gatignol |
| Abstract |
HIV-1 translation is modulated by the activation of the interferon (IFN)-inducible Protein Kinase RNA-activated (PKR). PKR phosphorylates its downstream targets, including the alpha subunit of the eukaryotic translation Initiation Factor 2 (eIF2α), which decreases viral replication. The PKR Activator (PACT) is known to activate PKR after a cellular stress. In lymphocytic cell lines, HIV-1 activates PKR only transiently and not when cells replicate the virus at high levels. The regulation of this activation is due to a combination of viral and cellular factors that have been only partially identified. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 55 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 30% |
| Student > Ph. D. Student | 8 | 14% |
| Student > Master | 6 | 11% |
| Student > Doctoral Student | 4 | 7% |
| Student > Bachelor | 3 | 5% |
| Other | 7 | 13% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 15 | 27% |
| Agricultural and Biological Sciences | 14 | 25% |
| Immunology and Microbiology | 6 | 11% |
| Neuroscience | 3 | 5% |
| Medicine and Dentistry | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 11 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2013.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Retrovirology
#1,079
of 1,273 outputs
Outputs of similar age
#159,247
of 210,820 outputs
Outputs of similar age from Retrovirology
#24
of 32 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,820 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.