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Promoter methylation and expression of TIMP3 gene in gastric cancer

Overview of attention for article published in Diagnostic Pathology, July 2013
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Title
Promoter methylation and expression of TIMP3 gene in gastric cancer
Published in
Diagnostic Pathology, July 2013
DOI 10.1186/1746-1596-8-110
Pubmed ID
Authors

ZhiYu Guan, Jun Zhang, ShiHui Song, DongQiu Dai

Abstract

Gastric carcinoma development is a multi-stage process that involves more than one gene. Aberrant changes in DNA methylation are considered as the third mechanism that leads to anti-oncogene inactivation, which plays an essential role in tumor development. In this study, we assessed the relationship among the aberrant methylation of the promoter CpG islands of tissue inhibitor of metalloproteinase 3 (TIMP3) gene, its protein expression, and the clinicopathological features of gastric adenocarcinoma.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 32%
Student > Ph. D. Student 7 23%
Student > Doctoral Student 2 6%
Student > Bachelor 2 6%
Researcher 2 6%
Other 3 10%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 26%
Agricultural and Biological Sciences 7 23%
Medicine and Dentistry 6 19%
Physics and Astronomy 1 3%
Nursing and Health Professions 1 3%
Other 2 6%
Unknown 6 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2013.
All research outputs
#18,347,414
of 22,721,584 outputs
Outputs from Diagnostic Pathology
#756
of 1,120 outputs
Outputs of similar age
#145,905
of 194,363 outputs
Outputs of similar age from Diagnostic Pathology
#15
of 24 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,120 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,363 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.