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Mendeley readers
| Title |
Arginine rich short linear motif of HIV-1 regulatory proteins inhibits Dicer dependent RNA interference
|
|---|---|
| Published in |
Retrovirology, September 2013
|
| DOI | 10.1186/1742-4690-10-97 |
| Pubmed ID | |
| Authors |
Sanket Singh Ponia, Sakshi Arora, Binod Kumar, Akhil C Banerjea |
| Abstract |
Arginine Rich Motif (ARM) of HIV-1 Tat and Rev are extensively studied linear motifs (LMs). They are already established as an inefficient bipartite nuclear localisation signal (NLS). The unusual passive diffusion of HIV-1 NLS tagged reporter proteins across the nucleus is due to an unknown competing functionality of ARM. Recent findings about the role of retroviral proteins as a suppressor of RNA interference (RNAi) involving their basic residues hint an interesting answer to this alternate functionality. The present work explores the role of HIV-1 ARM as a uniquely evolved viral motif to combat Dicer dependent RNAi. |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 26% |
| Student > Ph. D. Student | 9 | 26% |
| Other | 3 | 9% |
| Student > Master | 3 | 9% |
| Student > Doctoral Student | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 6 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 32% |
| Agricultural and Biological Sciences | 8 | 24% |
| Medicine and Dentistry | 2 | 6% |
| Immunology and Microbiology | 2 | 6% |
| Mathematics | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 7 | 21% |