Title |
Lipid peroxidation and antioxidant enzymes activity in Plasmodium vivax malaria patients evolving with cholestatic jaundice
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Published in |
Malaria Journal, September 2013
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DOI | 10.1186/1475-2875-12-315 |
Pubmed ID | |
Authors |
Camila Fabbri, Rita de Cássia Mascarenhas-Netto, Pritesh Lalwani, Gisely C Melo, Belisa ML Magalhães, Márcia AA Alexandre, Marcus VG Lacerda, Emerson S Lima |
Abstract |
Plasmodium vivax infection has been considered a benign and self-limiting disease, however, recent studies highlight the association between vivax malaria and life-threatening manifestations. Increase in reactive oxygen species has already been described in vivax malaria, as a result of the increased metabolic rate triggered by the multiplying parasite, and large quantities of toxic redox-active byproducts generated. The present study aimed to study the oxidative stress responses in patients infected with P. vivax, who developed jaundice (hyperbilirubinaemia) in the course of the disease, a common clinical complication related to this species. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 4% |
Unknown | 54 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 21% |
Student > Master | 8 | 14% |
Student > Doctoral Student | 6 | 11% |
Student > Bachelor | 6 | 11% |
Other | 6 | 11% |
Other | 13 | 23% |
Unknown | 5 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 29% |
Agricultural and Biological Sciences | 14 | 25% |
Immunology and Microbiology | 6 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Other | 6 | 11% |
Unknown | 6 | 11% |