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Method validation of circulating tumour cell enumeration at low cell counts

Overview of attention for article published in BMC Cancer, September 2013
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Title
Method validation of circulating tumour cell enumeration at low cell counts
Published in
BMC Cancer, September 2013
DOI 10.1186/1471-2407-13-415
Pubmed ID
Authors

Jeffrey Cummings, Karen Morris, Cong Zhou, Robert Sloane, Matt Lancashire, Daniel Morris, Stephen Bramley, Matt Krebs, Leila Khoja, Caroline Dive

Abstract

Circulating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (<10 cells/7.5 ml). Consequently, we have conducted method validation of the CellSearch™ system focusing on clinical samples containing CTC in the cut-off region.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Netherlands 1 2%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 24%
Researcher 8 19%
Other 7 17%
Student > Master 5 12%
Student > Bachelor 1 2%
Other 5 12%
Unknown 6 14%
Readers by discipline Count As %
Medicine and Dentistry 11 26%
Agricultural and Biological Sciences 8 19%
Biochemistry, Genetics and Molecular Biology 4 10%
Mathematics 3 7%
Nursing and Health Professions 3 7%
Other 5 12%
Unknown 8 19%