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PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation

Overview of attention for article published in Genome Biology, September 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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4 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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182 Dimensions

Readers on

mendeley
175 Mendeley
citeulike
1 CiteULike
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Title
PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation
Published in
Genome Biology, September 2013
DOI 10.1186/gb-2013-14-9-r99
Pubmed ID
Authors

Lorenzo de la Rica, Javier Rodríguez-Ubreva, Mireia García, Abul BMMK Islam, José M Urquiza, Henar Hernando, Jesper Christensen, Kristian Helin, Carmen Gómez-Vaquero, Esteban Ballestar

Abstract

DNA methylation is a key epigenetic mechanism for driving and stabilizing cell-fate decisions. Local deposition and removal of DNA methylation are tightly coupled with transcription factor binding, although the relationship varies with the specific differentiation process. Conversion of monocytes to osteoclasts is a unique terminal differentiation process within the hematopoietic system. This differentiation model is relevant to autoimmune disease and cancer, and there is abundant knowledge on the sets of transcription factors involved.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
Spain 2 1%
United Kingdom 2 1%
Unknown 166 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 26%
Researcher 40 23%
Student > Master 18 10%
Student > Bachelor 17 10%
Student > Doctoral Student 11 6%
Other 24 14%
Unknown 20 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 52 30%
Agricultural and Biological Sciences 50 29%
Medicine and Dentistry 19 11%
Immunology and Microbiology 15 9%
Computer Science 5 3%
Other 10 6%
Unknown 24 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2013.
All research outputs
#8,475,150
of 25,374,917 outputs
Outputs from Genome Biology
#3,479
of 4,467 outputs
Outputs of similar age
#71,698
of 210,956 outputs
Outputs of similar age from Genome Biology
#26
of 43 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.