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Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitrousage of alternative coreceptors during progressive HIV-1 subtype C infection

Overview of attention for article published in Retrovirology, September 2013
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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39 Mendeley
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Title
Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitrousage of alternative coreceptors during progressive HIV-1 subtype C infection
Published in
Retrovirology, September 2013
DOI 10.1186/1742-4690-10-98
Pubmed ID
Authors

Kieran Cashin, Martin R Jakobsen, Jasminka Sterjovski, Michael Roche, Anne Ellett, Jacqueline K Flynn, Katharina Borm, Maelenn Gouillou, Melissa J Churchill, Paul R Gorry

Abstract

Human immunodeficiency virus type 1 (HIV-1) subtype C (C-HIV) is spreading rapidly and is now responsible for >50% of HIV-1 infections worldwide, and >95% of infections in southern Africa and central Asia. These regions are burdened with the overwhelming majority of HIV-1 infections, yet we know very little about the pathogenesis of C-HIV. In addition to CCR5 and CXCR4, the HIV-1 envelope glycoproteins (Env) may engage a variety of alternative coreceptors for entry into transfected cells. Whilst alternative coreceptors do not appear to have a broad role in mediating the entry of HIV-1 into primary cells, characterizing patterns of alternative coreceptor usage in vitro can provide valuable insights into mechanisms of Env-coreceptor engagement that may be important for HIV-1 pathogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 26%
Researcher 9 23%
Student > Ph. D. Student 7 18%
Student > Postgraduate 3 8%
Student > Bachelor 2 5%
Other 4 10%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 31%
Biochemistry, Genetics and Molecular Biology 7 18%
Immunology and Microbiology 6 15%
Medicine and Dentistry 6 15%
Computer Science 2 5%
Other 2 5%
Unknown 4 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2013.
All research outputs
#13,316,898
of 22,721,584 outputs
Outputs from Retrovirology
#614
of 1,104 outputs
Outputs of similar age
#93,047
of 179,662 outputs
Outputs of similar age from Retrovirology
#14
of 31 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,104 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,662 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.