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MicroRNA-145 regulates oncolytic herpes simplex virus-1 for selective killing of human non-small cell lung cancer cells

Overview of attention for article published in Virology Journal, July 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

patent
12 patents
googleplus
1 Google+ user

Citations

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42 Dimensions

Readers on

mendeley
45 Mendeley
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Title
MicroRNA-145 regulates oncolytic herpes simplex virus-1 for selective killing of human non-small cell lung cancer cells
Published in
Virology Journal, July 2013
DOI 10.1186/1743-422x-10-241
Pubmed ID
Authors

Jhy-Ming Li, Kuo-Chin Kao, Li-Fu Li, Tsung-Ming Yang, Chean-Ping Wu, Yan-Ming Horng, William WG Jia, Cheng-Ta Yang

Abstract

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide, and novel treatment modalities to improve the prognosis of patients with advanced disease are highly desirable. Oncolytic virotherapy is a promising approach for the treatment of advanced NSCLC. MicroRNAs (miRNAs) may be a factor in the regulation of tumor-specific viral replication. The purpose of this study was to investigate whether miRNA-145 regulated oncolytic herpes simplex virus-1 (HSV-1) can selectively kill NSCLC cells with reduced collateral damage to normal cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Bachelor 9 20%
Student > Ph. D. Student 8 18%
Professor 3 7%
Student > Doctoral Student 2 4%
Other 6 13%
Unknown 8 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 31%
Biochemistry, Genetics and Molecular Biology 10 22%
Medicine and Dentistry 6 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Veterinary Science and Veterinary Medicine 1 2%
Other 2 4%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2024.
All research outputs
#1,689,534
of 23,504,791 outputs
Outputs from Virology Journal
#120
of 3,109 outputs
Outputs of similar age
#15,124
of 199,657 outputs
Outputs of similar age from Virology Journal
#3
of 77 outputs
Altmetric has tracked 23,504,791 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,109 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.9. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,657 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.