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Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3

Overview of attention for article published in Fluids and Barriers of the CNS, September 2013
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Title
Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3
Published in
Fluids and Barriers of the CNS, September 2013
DOI 10.1186/2045-8118-10-27
Pubmed ID
Authors

Miguel Alejandro Lopez-Ramirez, David Kingsley Male, Chunfang Wang, Basil Sharrack, Dongsheng Wu, Ignacio Andres Romero

Abstract

The human cerebral microvascular endothelial cell line, hCMEC/D3, has been used extensively to model the blood-brain barrier (BBB) in vitro. Recently, we reported that cytokine-treatment induced loss of brain endothelial barrier properties. In this study, we further determined the gene expression pattern of hCMEC/D3 cells in response to activation with TNFα and IFNγ.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 68 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 25%
Researcher 13 19%
Student > Master 9 13%
Student > Doctoral Student 7 10%
Student > Bachelor 6 9%
Other 8 12%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 26%
Biochemistry, Genetics and Molecular Biology 15 22%
Medicine and Dentistry 8 12%
Neuroscience 8 12%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Other 3 4%
Unknown 12 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2013.
All research outputs
#18,347,414
of 22,721,584 outputs
Outputs from Fluids and Barriers of the CNS
#269
of 358 outputs
Outputs of similar age
#150,101
of 201,863 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#1
of 1 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 358 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,863 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them