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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Calorie restriction and cancer prevention: a mechanistic perspective
|
|---|---|
| Published in |
Cancer & Metabolism, March 2013
|
| DOI | 10.1186/2049-3002-1-10 |
| Pubmed ID | |
| Authors |
Stephen D Hursting, Sarah M Dunlap, Nikki A Ford, Marcie J Hursting, Laura M Lashinger |
| Abstract |
Calorie restriction (CR) is one of the most potent broadly acting dietary interventions for inducing weight loss and for inhibiting cancer in experimental models. Translation of the mechanistic lessons learned from research on CR to cancer prevention strategies in human beings is important given the high prevalence of excess energy intake, obesity, and metabolic syndrome in many parts of the world and the established links between obesity-associated metabolic perturbations and increased risk or progression of many types of cancer. This review synthesizes findings on the biological mechanisms underlying many of the anticancer effects of CR, with emphasis on the impact of CR on growth factor signaling pathways, inflammation, cellular and systemic energy homeostasis pathways, vascular perturbations, and the tumor microenvironment. These CR-responsive pathways and processes represent targets for translating CR research into effective cancer prevention strategies in human beings. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| Saudi Arabia | 1 | 13% |
| Venezuela, Bolivarian Republic of | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 50% |
| Scientists | 2 | 25% |
| Practitioners (doctors, other healthcare professionals) | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 176 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Pakistan | 1 | <1% |
| Sweden | 1 | <1% |
| United Kingdom | 1 | <1% |
| Belgium | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 170 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 15% |
| Student > Master | 26 | 15% |
| Student > Bachelor | 26 | 15% |
| Researcher | 20 | 11% |
| Other | 14 | 8% |
| Other | 32 | 18% |
| Unknown | 32 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 24% |
| Medicine and Dentistry | 39 | 22% |
| Biochemistry, Genetics and Molecular Biology | 30 | 17% |
| Nursing and Health Professions | 5 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 12 | 7% |
| Unknown | 42 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2023.
All research outputs
#1,397,142
of 23,565,002 outputs
Outputs from Cancer & Metabolism
#14
of 209 outputs
Outputs of similar age
#11,127
of 196,497 outputs
Outputs of similar age from Cancer & Metabolism
#1
of 8 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 209 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,497 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them