Title |
Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population
|
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Published in |
Journal of Translational Medicine, September 2013
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DOI | 10.1186/1479-5876-11-220 |
Pubmed ID | |
Authors |
Diana Torres-García, Alfredo Cruz-Lagunas, Ma Cecilia García-Sancho Figueroa, Rosario Fernández-Plata, Renata Baez-Saldaña, Criselda Mendoza-Milla, Rodrigo Barquera, Aida Carrera-Eusebio, Salomón Ramírez-Bravo, Lizeth Campos, Javier Angeles, Gilberto Vargas-Alarcón, Julio Granados, Radha Gopal, Shabaana A Khader, Edmond J Yunis, Joaquin Zuñiga |
Abstract |
The control of Mycobacterium tuberculosis (Mtb) infection begins with the recognition of mycobacterial structural components by toll like receptors (TLRs) and other pattern recognition receptors. Our objective was to determine the influence of TLRs polymorphisms in the susceptibility to develop tuberculosis (TB) in Amerindian individuals from a rural area of Oaxaca, Mexico with high TB incidence. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 1% |
Sudan | 1 | 1% |
Unknown | 67 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 25% |
Student > Master | 13 | 19% |
Student > Ph. D. Student | 6 | 9% |
Student > Postgraduate | 5 | 7% |
Student > Doctoral Student | 4 | 6% |
Other | 9 | 13% |
Unknown | 15 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 26% |
Medicine and Dentistry | 12 | 17% |
Immunology and Microbiology | 7 | 10% |
Biochemistry, Genetics and Molecular Biology | 5 | 7% |
Nursing and Health Professions | 3 | 4% |
Other | 6 | 9% |
Unknown | 18 | 26% |