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Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model

Overview of attention for article published in Stem Cell Research & Therapy, July 2013
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Title
Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model
Published in
Stem Cell Research & Therapy, July 2013
DOI 10.1186/scrt227
Pubmed ID
Authors

Hui Yang, Zhao Hong Xie, Li Fei Wei, Hong Na Yang, Shao Nan Yang, Zheng Yu Zhu, Ping Wang, Cui Ping Zhao, Jian Zhong Bi

Abstract

Cell therapy is a potential therapeutic approach for neurodegenerative disorders, such as Alzheimer disease (AD). Neuronal differentiation of stem cells before transplantation is a promising procedure for cell therapy. However, the therapeutic impact and mechanisms of action of neuron-like cells differentiated from human umbilical cord mesenchymal stem cells in AD have not been determined.

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Poland 1 1%
Singapore 1 1%
Unknown 95 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 21%
Researcher 16 16%
Student > Master 14 14%
Student > Bachelor 13 13%
Student > Doctoral Student 5 5%
Other 9 9%
Unknown 20 20%
Readers by discipline Count As %
Medicine and Dentistry 17 17%
Neuroscience 16 16%
Biochemistry, Genetics and Molecular Biology 15 15%
Agricultural and Biological Sciences 14 14%
Engineering 3 3%
Other 5 5%
Unknown 28 29%