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Pathway-based outlier method reveals heterogeneous genomic structure of autism in blood transcriptome

Overview of attention for article published in BMC Medical Genomics, September 2013
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Title
Pathway-based outlier method reveals heterogeneous genomic structure of autism in blood transcriptome
Published in
BMC Medical Genomics, September 2013
DOI 10.1186/1755-8794-6-34
Pubmed ID
Authors

Malcolm G Campbell, Isaac S Kohane, Sek Won Kong

Abstract

Decades of research strongly suggest that the genetic etiology of autism spectrum disorders (ASDs) is heterogeneous. However, most published studies focus on group differences between cases and controls. In contrast, we hypothesized that the heterogeneity of the disorder could be characterized by identifying pathways for which individuals are outliers rather than pathways representative of shared group differences of the ASD diagnosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Spain 2 4%
Netherlands 1 2%
Germany 1 2%
Finland 1 2%
Unknown 42 86%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 29%
Researcher 8 16%
Student > Master 5 10%
Student > Doctoral Student 4 8%
Student > Bachelor 3 6%
Other 9 18%
Unknown 6 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 31%
Biochemistry, Genetics and Molecular Biology 8 16%
Sports and Recreations 3 6%
Psychology 3 6%
Medicine and Dentistry 3 6%
Other 8 16%
Unknown 9 18%