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X Demographics
Mendeley readers
Attention Score in Context
Title |
Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases
|
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Published in |
Radiation Oncology, September 2013
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DOI | 10.1186/1748-717x-8-209 |
Pubmed ID | |
Authors |
Luis L Rojas-Puentes, Marcelino Gonzalez-Pinedo, Alejando Crismatt, Alette Ortega-Gomez, Carlos Gamboa-Vignolle, Rodrigo Nuñez-Gomez, Yusmiren Dorantes-Gallareta, Claudia Arce-Salinas, Oscar Arrieta |
Abstract |
Chloroquine (CLQ), an antimalarial drug, has a lysosomotropic effect associated with increased radiationsensibility, which is mediated by the leakage of hydrolytic enzymes, increased apoptosis, autophagy and increased oxidative stress in vitro. In this phase II study, we evaluated the efficacy and safety of radiosensibilization using CLQ concomitant with 30 Gray (Gy) of whole-brain irradiation (WBI) to treat patients with brain metastases (BM) from solid tumors. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 107 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 17% |
Researcher | 16 | 15% |
Student > Master | 11 | 10% |
Student > Ph. D. Student | 10 | 9% |
Student > Doctoral Student | 5 | 5% |
Other | 18 | 17% |
Unknown | 29 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 25% |
Biochemistry, Genetics and Molecular Biology | 10 | 9% |
Nursing and Health Professions | 7 | 7% |
Agricultural and Biological Sciences | 7 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
Other | 16 | 15% |
Unknown | 35 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2013.
All research outputs
#19,806,316
of 24,338,161 outputs
Outputs from Radiation Oncology
#1,454
of 2,086 outputs
Outputs of similar age
#152,179
of 202,448 outputs
Outputs of similar age from Radiation Oncology
#37
of 43 outputs
Altmetric has tracked 24,338,161 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,086 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,448 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.