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A reappraisal of the mucoactive activity and clinical efficacy of bromhexine

Overview of attention for article published in Multidisciplinary Respiratory Medicine, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#48 of 265)
  • Good Attention Score compared to outputs of the same age (79th percentile)

Mentioned by

twitter
9 tweeters
wikipedia
4 Wikipedia pages

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
86 Mendeley
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Title
A reappraisal of the mucoactive activity and clinical efficacy of bromhexine
Published in
Multidisciplinary Respiratory Medicine, March 2017
DOI 10.1186/s40248-017-0088-1
Pubmed ID
Authors

Alessandro Zanasi, Massimiliano Mazzolini, Ahmad Kantar

Abstract

Since its introduction to the market in 1963, bromhexine, an over-the-counter drug, has been investigated for its activity in animal models and in humans with diverse respiratory conditions. Bromhexine is a derivate of the Adhatoda vasica plant used in some countries for the treatment of various respiratory diseases. Bromhexine has been found to enhance the secretion of various mucus components by modifying the physicochemical characteristics of mucus. These changes, in turn, increase mucociliary clearance and reduce cough. Principal clinical research studies were primarily developed in an era when stringent methodological approaches and good clinical practices were not developed yet. Clinical studies were conducted mainly in patients with chronic bronchitis and in patients with various respiratory diseases, and demonstrated the efficacy of bromhexine in improving respiratory symptoms. Furthermore, the co-administration of antibiotics with bromhexine amplified the actions of the antibiotic. Although the clinical evidence shows only modest but positive results, bromhexine is indicated for its mucoactive activity. Larger trials with adequate methodology are required to identify when treatment with bromhexine can improve clinical outcomes.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 15%
Student > Bachelor 12 14%
Student > Ph. D. Student 11 13%
Researcher 6 7%
Student > Doctoral Student 5 6%
Other 9 10%
Unknown 30 35%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 20 23%
Medicine and Dentistry 16 19%
Biochemistry, Genetics and Molecular Biology 7 8%
Chemistry 2 2%
Agricultural and Biological Sciences 2 2%
Other 8 9%
Unknown 31 36%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2021.
All research outputs
#2,867,242
of 18,838,632 outputs
Outputs from Multidisciplinary Respiratory Medicine
#48
of 265 outputs
Outputs of similar age
#56,874
of 276,677 outputs
Outputs of similar age from Multidisciplinary Respiratory Medicine
#1
of 1 outputs
Altmetric has tracked 18,838,632 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 265 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,677 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them