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Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse

Overview of attention for article published in Arthritis Research & Therapy, September 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

patent
2 patents

Citations

dimensions_citation
35 Dimensions

Readers on

mendeley
57 Mendeley
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Title
Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse
Published in
Arthritis Research & Therapy, September 2013
DOI 10.1186/ar4319
Pubmed ID
Authors

Fabia Doll, Kathrin Schwager, Teresa Hemmerle, Dario Neri

Abstract

Etanercept is a fusion protein consisting of the soluble portion of the p75-tumor necrosis factor receptor (TNFR) and the Fc fragment of human IgG1, which is often used for the treatment of patients with rheumatoid arthritis. F8-IL10 is a human immunocytokine based on the F8 antibody and interleukin-10, which is currently being investigated in rheumatoid arthritis with promising clinical results. We have aimed at expressing murine versions of these two fusion proteins, in order to assess their pharmaceutical performance in the collagen-induced model of rheumatoid arthritis in the mouse.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 25%
Student > Master 10 18%
Student > Ph. D. Student 7 12%
Professor 5 9%
Student > Bachelor 4 7%
Other 9 16%
Unknown 8 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 23%
Agricultural and Biological Sciences 13 23%
Immunology and Microbiology 6 11%
Medicine and Dentistry 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 6 11%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2017.
All research outputs
#5,446,994
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#1,264
of 3,381 outputs
Outputs of similar age
#46,370
of 216,595 outputs
Outputs of similar age from Arthritis Research & Therapy
#15
of 67 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 216,595 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.