Title |
H9N2 avian influenza infection altered expression pattern of Sphiogosine-1-phosphate Receptor 1 in BALB/c mice
|
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Published in |
Virology Journal, September 2013
|
DOI | 10.1186/1743-422x-10-296 |
Pubmed ID | |
Authors |
Shuang Tong, Jin Tian, Heng Wang, Zhiqiang Huang, Meng Yu, Lingshuang Sun, Rongchang Liu, Ming Liao, Zhangyong Ning |
Abstract |
The pathological damage inflicted by virulent AIV strains is often caused by inducing a positive feedback loop of cytokines in immune cells that cause excessive inflammation. Previous research has shown that a G protein-coupled receptor, sphingosine-1-phosphate receptor 1 (S1PR1), plays a crucial role in the development of excessive inflammation in influenza virus infection (Cell 146:861-862, 2011; Cell 146:980-991, 2011). BALB/c mice are common laboratory animals used in research of influenza virus; however the effects of influenza infections on expression patterns of S1PR1 in mice are unknown. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 25% |
Unknown | 6 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 88% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 21% |
Student > Bachelor | 3 | 13% |
Student > Master | 3 | 13% |
Researcher | 3 | 13% |
Professor | 2 | 8% |
Other | 2 | 8% |
Unknown | 6 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 21% |
Veterinary Science and Veterinary Medicine | 4 | 17% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Immunology and Microbiology | 2 | 8% |
Other | 3 | 13% |
Unknown | 6 | 25% |