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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice
|
|---|---|
| Published in |
Molecular Autism, October 2013
|
| DOI | 10.1186/2040-2392-4-35 |
| Pubmed ID | |
| Authors |
Travis M Kerr, Christopher L Muller, Mahfuzur Miah, Christopher S Jetter, Rita Pfeiffer, Charisma Shah, Nicole Baganz, George M Anderson, Jacqueline N Crawley, James S Sutcliffe, Randy D Blakely, Jeremy Veenstra-VanderWeele |
| Abstract |
Previously, we identified multiple, rare serotonin (5-HT) transporter (SERT) variants in children with autism spectrum disorder (ASD). Although in our study the SERT Ala56 variant was over-transmitted to ASD probands, it was also seen in some unaffected individuals, suggesting that associated ASD risk is influenced by the epistatic effects of other genetic variation. Subsequently, we established that mice expressing the SERT Ala56 variant on a 129S6/S4 genetic background display multiple biochemical, physiological and behavioral changes, including hyperserotonemia, altered 5-HT receptor sensitivity, and altered social, communication, and repetitive behavior. Here we explore the effects of genetic background on SERT Ala56 knock-in phenotypes. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 20% |
| Belgium | 1 | 20% |
| France | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 4% |
| Unknown | 77 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 30% |
| Student > Ph. D. Student | 13 | 16% |
| Student > Master | 6 | 8% |
| Student > Bachelor | 5 | 6% |
| Student > Doctoral Student | 3 | 4% |
| Other | 9 | 11% |
| Unknown | 20 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 24% |
| Neuroscience | 12 | 15% |
| Psychology | 6 | 8% |
| Medicine and Dentistry | 6 | 8% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Other | 9 | 11% |
| Unknown | 23 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2021.
All research outputs
#3,841,133
of 23,862,493 outputs
Outputs from Molecular Autism
#326
of 688 outputs
Outputs of similar age
#34,318
of 209,894 outputs
Outputs of similar age from Molecular Autism
#5
of 13 outputs
Altmetric has tracked 23,862,493 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 688 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.5. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,894 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.