Title |
Investigating silent strokes in hypertensives: a magnetic resonance imaging study (ISSYS): rationale and protocol design
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Published in |
BMC Neurology, October 2013
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DOI | 10.1186/1471-2377-13-130 |
Pubmed ID | |
Authors |
Iolanda Riba-Llena, Carmen Ioana Jarca, Xavier Mundet, Jose L Tovar, Francesc Orfila, Antonio López-Rueda, Cristina Nafría, Jose L Fernández, Xavier Castañé, Mar Domingo, José Álvarez-Sabín, Inés Fernández-Cortiñas, Olga Maisterra, Joan Montaner, Pilar Delgado |
Abstract |
Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover, they are independently associated with the risk of future stroke and cognitive decline.Despite these numbers and the clinical consequences of silent brain infarcts, their prevalence in Mediterranean populations is not well known and their role as predictors of future cerebrovascular and cardiovascular events in hypertensive remains to be determined.ISSYS (Investigating Silent Strokes in Hypertensives: a magnetic resonance imaging study) is an observational cross-sectional and longitudinal study aimed to: 1- determine the prevalence of silent cerebrovascular infarcts in a large cohort of 1000 hypertensives and to study their associated factors and 2-to study their relationship with the risk of future stroke and cognitive decline. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Egypt | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Cuba | 2 | 1% |
Brazil | 1 | <1% |
United Kingdom | 1 | <1% |
Sri Lanka | 1 | <1% |
Spain | 1 | <1% |
Unknown | 140 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 27 | 18% |
Researcher | 20 | 14% |
Student > Ph. D. Student | 18 | 12% |
Student > Bachelor | 17 | 12% |
Other | 9 | 6% |
Other | 26 | 18% |
Unknown | 29 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 49 | 34% |
Nursing and Health Professions | 13 | 9% |
Neuroscience | 9 | 6% |
Biochemistry, Genetics and Molecular Biology | 5 | 3% |
Agricultural and Biological Sciences | 4 | 3% |
Other | 26 | 18% |
Unknown | 40 | 27% |