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Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway

Overview of attention for article published in Cell Communication and Signaling, October 2013
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Title
Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway
Published in
Cell Communication and Signaling, October 2013
DOI 10.1186/1478-811x-11-74
Pubmed ID
Authors

Kwang Hwan Park, Boryung Park, Dong Suk Yoon, Seung-Hyun Kwon, Dong Min Shin, Jin Woo Lee, Hyun Gyu Lee, Jae-Hyuck Shim, Jeon Han Park, Jae Myun Lee

Abstract

Zinc, an essential trace element, inhibits osteoclast differentiation in vitro and in vivo. The molecular mechanism for the inhibitory effect of zinc, however, is poorly understood. The purpose of this study was to investigate the effect of zinc and determine its molecular mechanism on receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis in mouse bone marrow-derived monocyte cells (BMMs) and RAW264.7 cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Japan 1 2%
China 1 2%
Unknown 50 94%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 9 17%
Student > Ph. D. Student 6 11%
Other 4 8%
Student > Bachelor 4 8%
Professor 4 8%
Other 13 25%
Unknown 13 25%
Readers by discipline Count As %
Medicine and Dentistry 14 26%
Agricultural and Biological Sciences 10 19%
Biochemistry, Genetics and Molecular Biology 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Materials Science 2 4%
Other 5 9%
Unknown 15 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2013.
All research outputs
#20,205,224
of 22,725,280 outputs
Outputs from Cell Communication and Signaling
#905
of 980 outputs
Outputs of similar age
#181,358
of 207,309 outputs
Outputs of similar age from Cell Communication and Signaling
#6
of 9 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 980 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,309 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.