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Mendeley readers
Attention Score in Context
| Title |
Regulation of the unfolded protein response by microRNAs
|
|---|---|
| Published in |
Cellular & Molecular Biology Letters, October 2013
|
| DOI | 10.2478/s11658-013-0106-z |
| Pubmed ID | |
| Authors |
Sylwia Bartoszewska, Kinga Kochan, Piotr Madanecki, Arkadiusz Piotrowski, Renata Ochocka, James Collawn, Rafal Bartoszewski |
| Abstract |
The unfolded protein response (UPR) is an adaptive response to the stress that is caused by an accumulation of misfolded proteins in the lumen of the endoplasmic reticulum (ER). It is an important component of cellular homeostasis. During ER stress, the UPR increases the protein-folding capacity of the endoplasmic reticulum to relieve the stress. Failure to recover leads to apoptosis. Specific cellular mechanisms are required for the cellular recovery phase after UPR activation. Using bioinformatics tools, we identified a number of microRNAs that are predicted to decrease the mRNA expression levels for a number of critical components of the UPR. In this review, we discuss the potential role of microRNAs as key regulators of this pathway and describe how microRNAs may play an essential role in turning off the UPR after the stress has subsided. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 40% |
| United States | 1 | 20% |
| Belgium | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 60% |
| Members of the public | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| United States | 1 | 1% |
| Russia | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 67 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 28% |
| Researcher | 15 | 21% |
| Student > Master | 6 | 8% |
| Student > Doctoral Student | 6 | 8% |
| Student > Bachelor | 4 | 6% |
| Other | 10 | 14% |
| Unknown | 11 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 29% |
| Agricultural and Biological Sciences | 21 | 29% |
| Medicine and Dentistry | 5 | 7% |
| Chemistry | 3 | 4% |
| Neuroscience | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 12 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2013.
All research outputs
#14,599,900
of 25,373,627 outputs
Outputs from Cellular & Molecular Biology Letters
#116
of 606 outputs
Outputs of similar age
#114,451
of 220,038 outputs
Outputs of similar age from Cellular & Molecular Biology Letters
#1
of 1 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 606 research outputs from this source. They receive a mean Attention Score of 2.8. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,038 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them