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Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate

Overview of attention for article published in Malaria Journal, October 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Mentioned by

twitter
6 X users

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
73 Mendeley
citeulike
1 CiteULike
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Title
Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate
Published in
Malaria Journal, October 2013
DOI 10.1186/1475-2875-12-359
Pubmed ID
Authors

Holly Matthews, Maryam Usman-Idris, Farid Khan, Martin Read, Niroshini Nirmalan

Abstract

Drug repurposing or repositioning refers to the usage of existing drugs in diseases other than those it was originally used for. For diseases like malaria, where there is an urgent need for active drug candidates, the strategy offers a route to significantly shorten the traditional drug development pipelines. Preliminary high-throughput screens on patent expired drug libraries have recently been carried out for Plasmodium falciparum. This study reports the systematic and objective further interrogation of selected compounds reported in these studies, to enable their repositioning as novel stand-alone anti-malarials or as combinatorial partners.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
India 1 1%
Ghana 1 1%
Unknown 69 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 25%
Researcher 11 15%
Student > Master 11 15%
Student > Bachelor 5 7%
Student > Postgraduate 4 5%
Other 12 16%
Unknown 12 16%
Readers by discipline Count As %
Chemistry 12 16%
Agricultural and Biological Sciences 11 15%
Pharmacology, Toxicology and Pharmaceutical Science 9 12%
Medicine and Dentistry 9 12%
Biochemistry, Genetics and Molecular Biology 8 11%
Other 9 12%
Unknown 15 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2014.
All research outputs
#7,376,686
of 22,725,280 outputs
Outputs from Malaria Journal
#2,382
of 5,549 outputs
Outputs of similar age
#69,533
of 209,651 outputs
Outputs of similar age from Malaria Journal
#42
of 88 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 5,549 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,651 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.