↓ Skip to main content

Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review

Overview of attention for article published in BMC Cancer, March 2017
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
60 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review
Published in
BMC Cancer, March 2017
DOI 10.1186/s12885-017-3199-3
Pubmed ID
Authors

Varun V. Varadarajan, Elizabeth K. Pace, Vatsal Patel, Raja Sawhney, Robert J. Amdur, Peter T. Dziegielewski

Abstract

Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid metastasis to the facial skeleton is performed. A 73-year-old female presented with metastatic FTC to the mandible and underwent total thyroidectomy, segmental mandibulectomy, bone impacted fibular free flap reconstruction, and adjuvant radioactive iodine treatment. The PubMed database was searched for literature describing thyroid cancer with facial skeleton metastasis using the key words "thyroid," "cancer," "carcinoma," "metastasis," and "malignancy" with "oral cavity," "maxilla," "mandible," "sinus," "paranasal," and "orbit." Reports that only involved the soft tissues were excluded. Systematic review revealed 59 cases of well-differentiated thyroid cancer with facial skeleton metastasis: 35 mandibular metastases (21 = FTC), 6 maxilla metastases (2 = FTC), 9 orbital metastases (4 = FTC), and 11 paranasal sinus metastases (7 = FTC). Treatment included surgery, RAI, external beam radiotherapy (XRT), or a combination of these modalities. The one, two, and five-year survival rates were 100%, 79%, and 16%, respectively. Facial skeleton metastasis of FTC is a rare clinical challenge. Optimal treatment appears to include total thyroidectomy and resection of involved structures with or without adjuvant treatment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 13%
Student > Postgraduate 7 12%
Student > Master 5 8%
Student > Doctoral Student 4 7%
Researcher 4 7%
Other 8 13%
Unknown 24 40%
Readers by discipline Count As %
Medicine and Dentistry 28 47%
Nursing and Health Professions 3 5%
Biochemistry, Genetics and Molecular Biology 2 3%
Veterinary Science and Veterinary Medicine 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 3 5%
Unknown 21 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2017.
All research outputs
#19,292,491
of 23,881,329 outputs
Outputs from BMC Cancer
#5,591
of 8,483 outputs
Outputs of similar age
#238,255
of 310,427 outputs
Outputs of similar age from BMC Cancer
#74
of 121 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,483 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,427 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 121 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.