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Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration

Overview of attention for article published in Breast Cancer Research, September 2013
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Title
Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration
Published in
Breast Cancer Research, September 2013
DOI 10.1186/bcr3487
Pubmed ID
Authors

Kristi Bray, Melissa Gillette, Jeanette Young, Elizabeth Loughran, Melissa Hwang, James Cooper Sears, Tracy Vargo-Gogola

Abstract

The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast tumors compared to normal breast tissue. Cdc42 regulates key processes that are critical for mammary gland morphogenesis and become disrupted during the development, progression, and metastasis of breast cancer. However, the contribution of Cdc42 to normal and neoplastic mammary gland development in vivo remains poorly understood. We were therefore interested in investigating the effects of Cdc42 overexpression on mammary gland morphogenesis as a first step toward understanding how its overexpression may contribute to mammary tumorigenesis.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 27%
Student > Master 12 20%
Student > Doctoral Student 5 8%
Student > Bachelor 5 8%
Researcher 5 8%
Other 3 5%
Unknown 14 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 37%
Biochemistry, Genetics and Molecular Biology 11 18%
Medicine and Dentistry 4 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Physics and Astronomy 2 3%
Other 3 5%
Unknown 16 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2013.
All research outputs
#17,285,036
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,534
of 2,052 outputs
Outputs of similar age
#137,109
of 218,618 outputs
Outputs of similar age from Breast Cancer Research
#21
of 37 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 218,618 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.