Title |
Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells
|
---|---|
Published in |
Stem Cell Research & Therapy, October 2013
|
DOI | 10.1186/scrt336 |
Pubmed ID | |
Authors |
Andreia Ribeiro, Paula Laranjeira, Sandrine Mendes, Isabel Velada, Cristiana Leite, Pedro Andrade, Francisco Santos, Ana Henriques, Mário Grãos, Carla M P Cardoso, António Martinho, M Luísa Pais, Cláudia Lobato da Silva, Joaquim Cabral, Hélder Trindade, Artur Paiva |
Abstract |
The ability to self-renew, be easily expanded in vitro and differentiate into different mesenchymal tissues, render mesenchymal stem cells (MSCs) an attractive therapeutic method for degenerative diseases. The subsequent discovery of their immunosuppressive ability encouraged clinical trials in graft-versus-host disease and auto-immune diseases. Despite sharing several immunophenotypic characteristics and functional capabilities, the differences between MSCs arising from different tissues are still unclear and the published data are conflicting. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | <1% |
France | 1 | <1% |
Brazil | 1 | <1% |
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 215 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 36 | 16% |
Researcher | 36 | 16% |
Student > Master | 31 | 14% |
Student > Bachelor | 26 | 12% |
Student > Postgraduate | 13 | 6% |
Other | 37 | 17% |
Unknown | 42 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 47 | 21% |
Medicine and Dentistry | 41 | 19% |
Biochemistry, Genetics and Molecular Biology | 37 | 17% |
Immunology and Microbiology | 15 | 7% |
Engineering | 8 | 4% |
Other | 21 | 10% |
Unknown | 52 | 24% |