Title |
Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues
|
---|---|
Published in |
BMC Medical Genomics, October 2013
|
DOI | 10.1186/1755-8794-6-38 |
Pubmed ID | |
Authors |
Aleksandra Pfeifer, Bartosz Wojtas, Malgorzata Oczko-Wojciechowska, Aleksandra Kukulska, Agnieszka Czarniecka, Markus Eszlinger, Thomas Musholt, Tomasz Stokowy, Michal Swierniak, Ewa Stobiecka, Dagmara Rusinek, Tomasz Tyszkiewicz, Monika Kowal, Michal Jarzab, Steffen Hauptmann, Dariusz Lange, Ralf Paschke, Barbara Jarzab |
Abstract |
Differential diagnosis between malignant follicular thyroid cancer (FTC) and benign follicular thyroid adenoma (FTA) is a great challenge for even an experienced pathologist and requires special effort. Molecular markers may potentially support a differential diagnosis between FTC and FTA in postoperative specimens. The purpose of this study was to derive molecular support for differential post-operative diagnosis, in the form of a simple multigene mRNA-based classifier that would differentiate between FTC and FTA tissue samples. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 29% |
Student > Ph. D. Student | 5 | 11% |
Professor | 4 | 9% |
Other | 4 | 9% |
Student > Bachelor | 3 | 7% |
Other | 8 | 18% |
Unknown | 8 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 42% |
Biochemistry, Genetics and Molecular Biology | 8 | 18% |
Agricultural and Biological Sciences | 4 | 9% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Nursing and Health Professions | 1 | 2% |
Other | 2 | 4% |
Unknown | 10 | 22% |