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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Killing of Serratia marcescens biofilms with chloramphenicol
|
|---|---|
| Published in |
Annals of Clinical Microbiology and Antimicrobials, March 2017
|
| DOI | 10.1186/s12941-017-0192-2 |
| Pubmed ID | |
| Authors |
Christopher Ray, Anukul T. Shenoy, Carlos J. Orihuela, Norberto González-Juarbe |
| Abstract |
Serratia marcescens is a Gram-negative bacterium with proven resistance to multiple antibiotics and causative of catheter-associated infections. Bacterial colonization of catheters mainly involves the formation of biofilm. The objectives of this study were to explore the susceptibility of S. marcescens biofilms to high doses of common antibiotics and non-antimicrobial agents. Biofilms formed by a clinical isolate of S. marcescens were treated with ceftriaxone, kanamycin, gentamicin, and chloramphenicol at doses corresponding to 10, 100 and 1000 times their planktonic minimum inhibitory concentration. In addition, biofilms were also treated with chemical compounds such as polysorbate-80 and ursolic acid. S. marcescens demonstrated susceptibility to ceftriaxone, kanamycin, gentamicin, and chloramphenicol in its planktonic form, however, only chloramphenicol reduced both biofilm biomass and biofilm viability. Polysorbate-80 and ursolic acid had minimal to no effect on either planktonic and biofilm grown S. marcescens. Our results suggest that supratherapeutic doses of chloramphenicol can be used effectively against established S. marcescens biofilms. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 14% |
| Venezuela, Bolivarian Republic of | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 2 | 29% |
| Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 87 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 25 | 29% |
| Researcher | 10 | 11% |
| Student > Master | 8 | 9% |
| Student > Ph. D. Student | 8 | 9% |
| Student > Doctoral Student | 3 | 3% |
| Other | 6 | 7% |
| Unknown | 27 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 18% |
| Agricultural and Biological Sciences | 13 | 15% |
| Medicine and Dentistry | 6 | 7% |
| Immunology and Microbiology | 5 | 6% |
| Chemistry | 3 | 3% |
| Other | 12 | 14% |
| Unknown | 32 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2021.
All research outputs
#7,165,723
of 25,706,302 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#137
of 681 outputs
Outputs of similar age
#105,882
of 324,123 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#6
of 31 outputs
Altmetric has tracked 25,706,302 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 681 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,123 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.