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Mendeley readers
| Title |
Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter
|
|---|---|
| Published in |
Journal of Neuroinflammation, October 2013
|
| DOI | 10.1186/1742-2094-10-121 |
| Pubmed ID | |
| Authors |
Nico Melzer, Gordon Hicking, Stefan Bittner, Nicole Bobak, Kerstin Göbel, Alexander M Herrmann, Heinz Wiendl, Sven G Meuth |
| Abstract |
Neural-antigen reactive cytotoxic CD8+ T cells contribute to neuronal dysfunction and degeneration in a variety of inflammatory CNS disorders. Facing excess numbers of target cells, CNS-invading CD8+ T cells cause neuronal cell death either via confined release of cytotoxic effector molecules towards neurons, or via spillover of cytotoxic effector molecules from 'leaky' immunological synapses and non-confined release by CD8+ T cells themselves during serial and simultaneous killing of oligodendrocytes or astrocytes. |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Ireland | 1 | 3% |
| Unknown | 35 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 27% |
| Student > Doctoral Student | 4 | 11% |
| Researcher | 4 | 11% |
| Other | 3 | 8% |
| Professor > Associate Professor | 3 | 8% |
| Other | 8 | 22% |
| Unknown | 5 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 22% |
| Medicine and Dentistry | 8 | 22% |
| Neuroscience | 4 | 11% |
| Biochemistry, Genetics and Molecular Biology | 3 | 8% |
| Immunology and Microbiology | 2 | 5% |
| Other | 4 | 11% |
| Unknown | 8 | 22% |