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A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies

Overview of attention for article published in Journal of Translational Medicine, October 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

twitter
2 X users
patent
1 patent
wikipedia
1 Wikipedia page

Citations

dimensions_citation
106 Dimensions

Readers on

mendeley
85 Mendeley
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Title
A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies
Published in
Journal of Translational Medicine, October 2013
DOI 10.1186/1479-5876-11-259
Pubmed ID
Authors

John J Nemunaitis, Karen A Small, Paul Kirschmeier, Da Zhang, Yali Zhu, Ying-Ming Jou, Paul Statkevich, Siu-Long Yao, Rajat Bannerji

Abstract

Dinaciclib, a small-molecule, cyclin-dependent kinase inhibitor, inhibits cell cycle progression and proliferation in various tumor cell lines in vitro. We conducted an open-label, dose-escalation study to determine the safety, tolerability, and bioactivity of dinaciclib in adults with advanced malignancies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Egypt 1 1%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 18%
Student > Bachelor 11 13%
Researcher 10 12%
Student > Master 7 8%
Other 6 7%
Other 9 11%
Unknown 27 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 15%
Agricultural and Biological Sciences 13 15%
Medicine and Dentistry 13 15%
Chemistry 5 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Other 10 12%
Unknown 26 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2020.
All research outputs
#5,240,498
of 25,374,647 outputs
Outputs from Journal of Translational Medicine
#914
of 4,635 outputs
Outputs of similar age
#45,517
of 223,621 outputs
Outputs of similar age from Journal of Translational Medicine
#14
of 93 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,635 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,621 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.