Title |
Genome-level analyses of Mycobacterium bovis lineages reveal the role of SNPs and antisense transcription in differential gene expression
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Published in |
BMC Genomics, October 2013
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DOI | 10.1186/1471-2164-14-710 |
Pubmed ID | |
Authors |
Paul Golby, Javier Nunez, Adam Witney, Jason Hinds, Michael A Quail, Stephen Bentley, Simon Harris, Noel Smith, R Glyn Hewinson, Stephen V Gordon |
Abstract |
Bovine tuberculosis (bTB) is a disease with major implications for animal welfare and productivity, as well as having the potential for zoonotic transmission. In Great Britain (GB) alone, controlling bTB costs in the region of £ 100 million annually, with the current control scheme seemingly unable to stop the inexorable spread of infection. One aspect that may be driving the epidemic is evolution of the causative pathogen, Mycobacterium bovis. To understand the underlying genetic changes that may be responsible for this evolution, we performed a comprehensive genome-level analyses of 4 M. bovis strains that encompass the main molecular types of the pathogen circulating in GB. |
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Malaysia | 1 | 3% |
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Demographic breakdown
Type | Count | As % |
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Members of the public | 11 | 37% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
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Ireland | 1 | 1% |
Unknown | 76 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 26% |
Student > Ph. D. Student | 12 | 16% |
Student > Master | 12 | 16% |
Student > Postgraduate | 7 | 9% |
Student > Bachelor | 5 | 6% |
Other | 12 | 16% |
Unknown | 9 | 12% |
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Medicine and Dentistry | 6 | 8% |
Veterinary Science and Veterinary Medicine | 4 | 5% |
Other | 7 | 9% |
Unknown | 12 | 16% |