Title |
The dermomyotome ventrolateral lip is essential for the hypaxial myotome formation
|
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Published in |
BMC Developmental Biology, October 2013
|
DOI | 10.1186/1471-213x-13-37 |
Pubmed ID | |
Authors |
Qin Pu, Aisha Abduelmula, Maryna Masyuk, Carsten Theiss, Dieter Schwandulla, Michael Hans, Ketan Patel, Beate Brand-Saberi, Ruijin Huang |
Abstract |
The myotome is the primitive skeletal muscle that forms within the embryonic metameric body wall. It can be subdivided into an epaxial and hypaxial domain. It has been shown that the formation of the epaxial myotome requires the dorsomedial lip of the dermomyotome (DML). Although the ventrolateral lip (VLL) of the dermomyotome is believed to be required for the formation of the hypaxial myotome, experimentally evidence for this statement still needs to be provided. Provision of such data would enable the resolution of a debate regarding the formation of the hypaxial dermomyotome. Two mechanisms have been proposed for this tissue. The first proposes that the intermediate dermomyotome undergoes cellular expansion thereby pushing the ventral lateral lip in a lateral direction (translocation). In contrast, the alternative view holds that the ventral lateral lip grows laterally. |
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Geographical breakdown
Country | Count | As % |
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France | 1 | 4% |
Unknown | 22 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 36% |
Researcher | 6 | 24% |
Student > Master | 2 | 8% |
Professor | 1 | 4% |
Lecturer > Senior Lecturer | 1 | 4% |
Other | 2 | 8% |
Unknown | 4 | 16% |
Readers by discipline | Count | As % |
---|---|---|
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Medicine and Dentistry | 2 | 8% |
Neuroscience | 1 | 4% |
Unknown | 4 | 16% |