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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Pathogenesis of Lyme Neuroborreliosis: From Infection to Inflammation
|
|---|---|
| Published in |
Molecular Medicine, March 2008
|
| DOI | 10.2119/2007-00091.rupprecht |
| Pubmed ID | |
| Authors |
Tobias A. Rupprecht, Uwe Koedel, Volker Fingerle, Hans-Walter Pfister |
| Abstract |
This review describes the current knowledge of the pathogenesis of acute Lyme neuroborreliosis (LNB), from invasion to inflammation of the central nervous system. Borrelia burgdorferi (B.b.) enters the host through a tick bite on the skin and may disseminate from there to secondary organs, including the central nervous system. To achieve this, B.b. first has to evade the hostile immune system. In a second step, the borrelia have to reach the central nervous system and cross the blood-brain barrier. Once in the cerebrospinal fluid (CSF), the spirochetes elicit an inflammatory response. We describe current knowledge about the infiltration of leukocytes into the CSF in LNB. In the final section, we discuss the mechanisms by which the spirochetal infection leads to the observed neural dysfunction. To conclude, we construct a stringent concept of the pathogenesis of LNB. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 162 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| United States | 2 | 1% |
| Russia | 2 | 1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 154 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 34 | 21% |
| Student > Bachelor | 26 | 16% |
| Student > Ph. D. Student | 18 | 11% |
| Student > Master | 16 | 10% |
| Student > Doctoral Student | 12 | 7% |
| Other | 31 | 19% |
| Unknown | 25 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 33% |
| Agricultural and Biological Sciences | 28 | 17% |
| Biochemistry, Genetics and Molecular Biology | 18 | 11% |
| Immunology and Microbiology | 13 | 8% |
| Mathematics | 2 | 1% |
| Other | 14 | 9% |
| Unknown | 33 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2019.
All research outputs
#5,630,689
of 22,727,570 outputs
Outputs from Molecular Medicine
#278
of 1,131 outputs
Outputs of similar age
#23,010
of 79,786 outputs
Outputs of similar age from Molecular Medicine
#7
of 16 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,131 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 79,786 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.