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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence
|
|---|---|
| Published in |
BMC Genomics, October 2013
|
| DOI | 10.1186/1471-2164-14-725 |
| Pubmed ID | |
| Authors |
Yury O Nunez, Jay M Truitt, Giorgio Gorini, Olga N Ponomareva, Yuri A Blednov, R Adron Harris, R Dayne Mayfield |
| Abstract |
Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind. MicroRNAs simultaneously target many transcripts and fine-tune the expression of genes through cooperative/combinatorial targeting. Therefore, they have a large regulatory potential that could widely impact development and progression of diseases, as well as contribute unpredicted collateral effects due to their natural, pathophysiological, or treatment-induced modulation. We support the viewpoint that whole mirnome-transcriptome interaction analysis is required to better understand the mechanisms and potential consequences of miRNA regulation and/or deregulation in relevant biological models. In this study, we tested the hypotheses that ethanol consumption induces changes in miRNA-mRNA interaction networks in the mouse frontal cortex and that some of the changes observed in the mouse are equivalent to changes in similar brain regions from human alcoholics. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| France | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 1% |
| Netherlands | 1 | 1% |
| Sweden | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 93 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 27% |
| Student > Ph. D. Student | 15 | 15% |
| Student > Master | 11 | 11% |
| Student > Doctoral Student | 9 | 9% |
| Student > Postgraduate | 8 | 8% |
| Other | 15 | 15% |
| Unknown | 13 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 38% |
| Biochemistry, Genetics and Molecular Biology | 17 | 18% |
| Neuroscience | 7 | 7% |
| Medicine and Dentistry | 7 | 7% |
| Immunology and Microbiology | 3 | 3% |
| Other | 9 | 9% |
| Unknown | 17 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2013.
All research outputs
#17,700,887
of 22,727,570 outputs
Outputs from BMC Genomics
#7,539
of 10,628 outputs
Outputs of similar age
#151,584
of 212,053 outputs
Outputs of similar age from BMC Genomics
#80
of 152 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,628 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,053 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.