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Mendeley readers
| Title |
Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon
|
|---|---|
| Published in |
Molecular Cancer, October 2013
|
| DOI | 10.1186/1476-4598-12-126 |
| Pubmed ID | |
| Authors |
Pramudita Ramadhina Prasetyanti, Cheryl Doreen Zimberlin, Michael Bots, Louis Vermeulen, Felipe De Sousa E Melo, Jan Paul Medema |
| Abstract |
Colon cancer stem cells are shown to be the self-renewing cells within a tumor that give rise to all lineages of more differentiated tumor cells. In this respect they are remarkably similar to their non-malignant counterparts that orchestrate the intestinal lining. This suggests that, despite the numerous genetic aberrations and morphological changes that have occurred during cancer initiation and progression, a remnant homeostatic regulation persists. |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| France | 2 | 2% |
| Poland | 1 | 1% |
| Unknown | 79 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 29% |
| Researcher | 14 | 17% |
| Student > Master | 14 | 17% |
| Student > Bachelor | 5 | 6% |
| Student > Postgraduate | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 10 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 38% |
| Biochemistry, Genetics and Molecular Biology | 23 | 27% |
| Medicine and Dentistry | 8 | 10% |
| Unspecified | 2 | 2% |
| Engineering | 2 | 2% |
| Other | 5 | 6% |
| Unknown | 12 | 14% |